Oystomato juice is a mixture of tomato juice and oyster juice. It is a parody of Clamato, which is a mixture of tomato juice and clam broth.
It appears in the episode iSpace Out when Spencer tries to drink a glass of Oystomato to see what it tastes like, despite the fact that, according to Carly, he hates both oysters and tomatoes (which Spencer forgot to take into consideration).
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